May 10, 2016



Wang L, Foer D, Bates DW, Boyce JA, Zhou L. Risk factors for hospitalization, intensive care and mortality among patients with asthma and COVID-19. J Allergy Clin Immunol. 2020 Jul 28:S0091-6749(20)31039-3. doi: 10.1016/j.jaci.2020.07.018. [Epub ahead of print]

Yang J, Landrum MB, Zhou L*, Busch AB*. Disparities in Outpatient Visits for Mental Health and/or Substance Use Disorders During the COVID-19 Surge and Partial Reopening in Massachusetts. General Hospital Psychiatry. 2020 Oct. ( *these authors contributed equally).

Wang D, Liu J, Zhou L, Bates DW, Li YC. Assessing the International Transferability of a Machine Learning Model for Detecting Medication Error in the General Internal Medicine Clinic: A Multicenter Preliminary Validation Study. Journal of Medical Internet Research. 2020.

Yang J, Wang L, Phaske NA, Wickner PG, Mancini CM, Blumenthal KG*, Zhou L*. Development and validation of a deep learning model to detect allergic reactions of safety event reports across hospitals: 2004-2019. JAMA Netw Open. 2020 (*these authors contributed equally).

Lacey RB, Wang L, Fu X, Wallace ZS, Long A, Zhang Y, Camargo CA, Blumenthal KG. COVID-19 severity in asthma patients: A multi-center matched cohort study. Journal of Asthma. In Press

Plasek JM, Tang C, Zhu Y, Huang Y, Bates DW. Following Data as it Crosses Borders During the COVID-19 Pandemic, Journal of the American Medical Informatics Association. 2020. doi:10.1093/jamia/ocaa063

Tang C, Plasek JM, Zhu Y, Huang Y. Data Sovereigns for the World Economy. Humanities & Social Sciences Communications. 2020. (in press)

Alvarez-Arango S, Yerneni S, Tang O, Zhou L, Mancini CM, Blackley SV, Keet CA, Blumenthal KG. Vancomycin. Vancomycin hypersensitivity reactions documented in electronic health records. J Allergy Clin Immunol Pract. 2020.doi:

Wang L, Miloslavsky E, Stone JH, Choi HK, Zhou L*, Wallace ZS*. Topic Modeling to Characterize the Natural History of ANCA- Associated Vasculitis from Clinical Notes: A Proof of Concept Study Seminars in Arthritis and Rheumatism. Seminars in Arthritis and Rheumatism. 2020 (*these authors contributed equally).

Shi D, Tang C, Blackley SV, Wang L, Yang J, He Y, Bennet S, Xiong Y, Shi X, Zhou L, Bates DW. An annotated dataset of tongue images supporting geriatric disease diagnosis. Data in Brief. 2020.

Phadke NA, Zhou L, Mancini CM, Yang J, Wang W, Wickner P, Fu X, Blumenthal KG. Allergic Reactions in Two Academic Medical Centers. J Gen Intern Med. 2020, In Press.

Korach ZT, Einbinder J, Kallenberg C, Yerneni S, Zhou L. Facilitating information extraction without annotated data using unsupervised and positive-unlabeled learning. AMIA Annu Symp Proc. 2020.

Blackley SV, MacPhaul E, Martin B, Song W, Suzuki J, Zhou L. Using Natural Language Processing and Machine Learning to Identify Hospitalized Patients with Opioid Use Disorder AMIA Annu Symp Proc. 2020.

Wang L, Blackley SV, Blumenthal KG, Yerneni S, Goss FR, Lo YC, Shah SN, Ortega CA, Korach ZT, Seger DL, Zhou L. A dynamic reaction picklist for improving allergy reaction documentation in the electronic health record. Journal of the American Medical Informatics Association. 2020 Jun 1;27(6):917-23.

Blackley SV, Schubert VD, Goss FR, Al Assad W, Garabedian, PM, Zhou, L. Physician Use of Speech Recognition versus Typing in Clinical Documentation: A Controlled Observational Study. Int J Med Inform. 2020 May 11. doi: 10.1016/j.ijmedinf.2020.104178. [Epub ahead of print]

Tang C, Plasek J, Shi X, Wan M, Zhang H, Kang MJ, Wang L, Dulgarian SM, Xiong Y, Ma J, Bates DW, Zhou. Estimating Time to Progression of Chronic Obstructive Pulmonary Disease with Tolerance. IEEE J Biomed Health Inform. 2020 May 4. doi: 10.1109/JBHI.2020.2992259. [Epub ahead of print]

Tang C, Plasek JM, Xiong Y, Bates DW, Zhou L. A Clustering Algorithm Based on Document Embedding to Identify Clinical Note Templates. Annals of Data Science:1-19. 2020.

Chang WC, Abe R, Anderson P, Anderson W, Ardern-Jones MR, Beachkofsky TM, Bellón T, Biala AK, Bouchard C, Cavalleri GL, Chapman N, Chodosh J, Choi HK, Cibotti RR, Divito SJ, Dewar K, Dehaeck U, Etminan M, Forbes D, Fuchs E, Goldman JL, Holmes JH 4th, Hope EA, Hung SI, Hsieh CL, Iovieno A, Jagdeo J, Kim MK, Koelle DM, Lacouture ME, Le Pallec S, Lehloenya RJ, Lim R, Lowe A, McCawley J, McCawley J, Micheletti RG, Mockenhaupt M, Niemeyer K, Norcross MA, Oboh D, Olteanu C, Pasieka HB, Peter J, Pirmohamed M, Rieder M, Saeed HN, Shear NH, Shieh C, Straus S, Sukasem C, Sung C, Trubiano JA, Tsou SY, Ueta M, Volpi S, Wan C, Wang H, Wang ZQ, Weintraub J, Whale C, Wheatley LM, Whyte-Croasdaile S, Williams KB, Wright G, Yeung SN, Zhou L, Chung WH, Phillips EJ, Carleton BC. SJS/TEN 2019: From science to translation. J Dermatol Sci. 2020 Mar 7. pii: S0923-1811(20)30064-5. doi: 10.1016/j.jdermsci.2020.02.003. [Epub ahead of print] Review. PubMed PMID: 32192826.

Spasić I, Uzuner Ö, Zhou L. Emerging clinical applications of text analytics. Int J Med Inform. 2020;134:103974. doi:10.1016/j.ijmedinf.2019.103974


Korach ZT, Yang J, Rossetti SC, Cato KD, Kang MJ, Knaplund C, Schnock KO, Garcia JP, Jia H, Schwartz JM, Zhou L. Mining clinical phrases from nursing notes to discover risk factors of patient deterioration. Int J Med Inform. 2019 Dec 14;135:104053. doi: 10.1016/j.ijmedinf.2019.104053. [Epub ahead of print]

Korach ZT, Cato KD, Collins SA, Kang MJ, Knaplund C, Dykes PC, Wang L, Schnock KO, Garcia JP, Jia H, Chang F, Schwartz JM, Zhou L Unsupervised Machine Learning of Topics Documented by Nurses about Hospitalized Patients Prior to a Rapid-Response Event. Appl Clin Inform. 2019 Oct;10(5):952-963. doi: 10.1055/s-0039-3401814. Epub 2019 Dec 18.

Kang MJ, Dykes PC, Korach TZ, Zhou L, Schnock KO, Thate J, Whalen K, Jia H, Schwartz J, Garcia JP, Knaplund C. Identifying nurses’ concern concepts about patient deterioration using a standard nursing terminology. Int J Med Inform.2020 Jan;133:104016. doi: 10.1016/j.ijmedinf.2019.104016. Epub 2019 Oct 31.

Zhang Z, Tang C, Plasek JM, Xiong Y, Kang MJ, Dykes PC, Bates DW, Zhou L. Data Reconstruction Based on Temporal Expressions in Clinical Notes. In2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) 2019 Nov 18 (pp. 1004-1008). IEEE.

Tang C, Plasek JM, Zhang H, Kang M, Sheng H, Xiong Y, Bates WB, Zhou L. A temporal visualization of chronic obstructive pulmonary disease progression using deep learning and unstructured clinical notes. BMC Med Inform Decis Mak 19, 258 (2019) doi:10.1186/s12911-019-0984-8.

Wang L, Sha L, Lakin JR, Bynum J, Bates DW, Hong P, Zhou L. Development and Validation of a Deep Learning Algorithm for Mortality Prediction in Selecting Patients With Dementia for Earlier Palliative Care Interventions. JAMA Netw Open. Published online July 12, 20192(7):e196972. doi:10.1001/jamanetworkopen.2019.6972

Goss FR, Blackley SV, Ortega CA, Kowalski LT, Landman AB, Lin CT, Meteer M, Bakes S, Gradwohl SC, Bates DW, Zhou L. A Clinician Survey of Using Speech Recognition for Clinical Documentation in the Electronic Health Record. Int J Med Inform. 2019 Jul 31;130:103938. doi: 10.1016/j.ijmedinf.2019.07.017.

Banerji A, Lai KH, Li Y, Saff RR, Camargo CA, Blumenthal KG, Zhou L. Natural Language Processing as a Novel Method to Study the Epidemiology of Allergic Drug Reactions. J Allergy Clin Immunol Pract. 2019 Dec 16. pii: S2213-2198(19)31028-1. doi: 10.1016/j.jaip.2019.12.007. [Epub ahead of print].

Wang SV, Patterson OV, Gagne JJ, Brown JS, Ball R, Jonsson P, Wright A, Zhou L, Goettsch W, Bate A. Transparent Reporting on Research Using Unstructured Electronic Health Record Data to Generate ‘Real World’ Evidence of Comparative Effectiveness and Safety. Drug Saf. 2019 Aug 26. doi: 10.1007/s40264-019-00851-0. [Epub ahead of print] PubMed PMID: 31452075.

Tang C, Zhu Y, Blackley SV, Plasek JM, Wang M, Zhou L, Ma J, Bates DW. “Visualizing Literature Review Theme Evolution on Timeline Maps: Comparison Across Disciplines,” in IEEE Access, vol. 7, pp. 90597-90607, 2019. doi: 10.1109/ACCESS.2019.2925706. URL:

Straub L, Gagne JJ, Maro JC, Nguyen MD, Beaulieu N, Brown JS, Kennedy A, Johnson M, Wright A, Zhou L, Wang SV. Evaluation of Use of Technologies to Facilitate Medical Chart Review. Drug Saf. 2019 May 20. doi: 10.1007/s40264-019-00838-x.

Deng F, Li MD, Wong A, Kowalski LT, Lai K, Digumarthy SR, Zhou L. Quality of documentation of contrast agent allergies in electronic health records. J Am Coll Radiol. 2019 Mar 4. pii: S1546-1440(19)30065-1. doi: 10.1016/j.jacr.2019.01.027. PMID: 30846398

Blumenthal KG, Topaz M, Zhou L, Harkenss T, Sa’adon R, Bar-Bachar O, Long AA. Mining Social Media Data to Assess the Risk of and Soft Tissue Infections from Allergen Immunotherapy. J Allergy Clin Immunol. 2019 Feb 2. pii: S0091-6749(19)30186-1. doi: 10.1016/j.jaci.2019.01.029. PMID: 30721764.

Dhopeshwarkar NV, Sheikh A, Doan R, Topaz M, Bates DW, Blumenthal KG, Zhou L. Drug-induced Anaphylaxis Documented in Electronic Health Records. J Allergy Clin Immunol Pract. 2019 Jan 1;7(1):103-11.  doi: 10.1016/j.jaip.2018.06.010.

Blackley SV, Huynh J, Wang L, Korach Z, Zhou L. Speech Recognition for Clinical Documentation from 1990 to 2018: A Systematic Review. J Am Med Inform Assoc. 2019 Apr 1;26(4):324-338. doi: 10.1093/jamia/ocy179. PMID: 30753666

Wong A, Seger DL, Lai KH, Goss FR, Blumenthal KG, Zhou L. Drug Hypersensitivity Reactions Documented in Electronic Health Records within a Large Health System. J Allergy Clin Immunol Pract. 2019 Apr;7(4):1253-1260.e3. doi: 10.1016/j.jaip.2018.11.023. Epub 2018 Dec 1. PMID: 3051336.


Tang C, Plasek J, Zhang H, Xiong Y, Bates DW, and Zhou L. A Deep Learning Approach to Handling Temporal Variation in Chronic Obstructive Pulmonary Disease Progression. In 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM): 502-509. Madrid, Spain.

Wong J, Horwitz MM, Zhou L, Toh S. Using Machine Learning to Identify Health Outcomes from Electronic Health Record Data. Curr Epidemiol Rep. 2018 Dec;5(4):331-342. doi: 10.1007/s40471-018-0165-9. Epub 2018 Sep 20. PMID: 30555773.

Wolfson AR, Zhou L, Li Y, Phadke NA, Chow OA, Blumenthal KG. Drug Rash Eosinophilia and Systemic Symptoms (DRESS) Syndrome Identified in the Electronic Health Record Allergy Module. The Journal of Allergy and Clinical Immunology: In Practice. 2018 Aug 31. pii: S2213-2198(18)30548-8. doi: 10.1016/j.jaip.2018.08.013.

Saff RR, Li Y, Santhanakrishnan N, Camargo CA Jr, Blumenthal KG, Zhou L, Banerji A. Identification of Inpatient Allergic Drug Reactions Using ICD-9-CM Codes. J Allergy Clin Immunol Pract. 2018 Jul 31. pii: S2213-2198(18)30457-4. doi: 10.1016/j.jaip.2018.07.022.

Zhou L, Blackley SV, Kowalski L, Doan R, Acker WW, Landman AB, Kontrient E, Mack D, Meteer M, Bates DW, Goss FR. Analysis of Errors in Dictated Clinical Documents Assisted by Speech Recognition Software and Professional Transcriptionists. JAMA Network Open. 2018 Jul 6;1(3):e180530-.

Topaz, M, Schaffer, A, Lai, KH, Korach Z, Einbinder J, Zhou L. Medical Malpractice Trends: Errors in Automated Speech Recognition. J Med Syst (2018) 42: 153.

Wang L, Lakin J, Riley C, Korach Z, Frain L, Zhou L. Disease Trajectories and End-of-Life Care for Dementias: Latent Topic Modeling and Trend Analysis Using Clinical Notes. AMIA Annu Symp Proc. 2018 Dec 5;2018:1056-1065. PMID: 30815148 PMCID: PMC6371376.

Tang C, Plasek JM, Xiong Y, Bates DW, Zhou L. Clustering Similar Clinical Documents in Electronic Health Records. International Conference on Data Science, ICDS 2018.

Wong A, Plasek JM, Montecalvo SP, Zhou, L. Natural language processing and its implications for the future of medication safety: a narrative review of recent advances and challenges. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 2018 Jun 9. doi: 10.1002/phar.2151

Blumenthal KG, Li Y, Acker WW, Chang Y, Banerji A, Ghaznavi S, Camargo CA, Zhou L. Multiple Drug Intolerance Syndrome and Multiple Drug Allergy Syndrome: Epidemiology and Associations with Anxiety and Depression. Allergy. 2018 Mar 25. doi: 10.1111/all.13440.

Topaz M, Schaffer A, Lai K, Korach T, Einbinder J, Zhou L. Malpractice cases involving allergy information in the electronic health records: implications for safer systems. Perspectives of Health Information Management. 2018: 1-9.

Goss FR, Lai KH, Topaz M, Acker WW, Kowalski L, Plasek JM, Blumenthal KG, Seger DL, Slight SP, Wah Fung K, Chang FY, Bates DW, Zhou L. A value set for documenting adverse reactions in electronic health records. J Am Med Inform Assoc. 2018 Jun 1;25(6):661-669. doi: 10.1093/jamia/ocx139.


Al Assad W, Topaz M, Tu J, Zhou L. Novel Application of Machine Learning to Evaluate the Adequacy of Information in Radiology Orders. 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 

Tang C, Zhang H, Lai K, She Y, Xiong Y, Zhou L.Developing a Regional Classifier to Track Patient Needs in Medical Literature Using Spiral Timelines on a Geographical Map. 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 

Lai K, Blackley S, Zhou L. Using Mutual Information Clustering to Discover Food Allergen Cross-Reactivity. 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). 

Lin KJ, Singer D, Glynn R, Blackley S, Zhou L, Liu J, Dube G, Oertel L, Schneeweiss S. Prediction Score for Anticoagulation Control Quality Among Older Adults. J Am Heart Assoc. 2017 Oct 5;6(10). pii: e006814. doi:10.1161/JAHA.117.006814. Review. PubMed PMID: 28982676; PubMed Central PMCID: PMC5721874.

Wang L, Plasek JM, Topaz M, Zhou L. Content and Trends in Medical Informatics Publications over the Past Two Decades. Stud Health Technol Inform. Stud Health Technol Inform. 2017;245:968-972.

Topaz M, Schaffer A, Acker W, Lai K, Korah Zfania T, Einbinder J, Zhou L. Health Information Technology Involved in Malpractice Cases: Trends Review and Opportunities for Safety Improvement. Stud Health Technol Inform. 2017;244:86. PubMed PMID: 29039390.

Tang C, Zhou L, Plasek J, Rozenblum R, Bates D. Comment Topic Evolution on a Cancer Institution’s Facebook Page. Applied clinical informatics 2017 Aug 23; 8(3):854-65. doi: 10.4338/ACI-2017-04-RA-0055. [published Online First: Epub Date]

Acker WW, Plasek JM, Blumenthal KG, Lai KH, Topaz M, Seger DL, Goss FR, Slight SP, Bates DW, Zhou L. Prevalence of Food Allergies and Intolerances Documented in Electronic Health Records. J Allergy Clin Immunol. 2017 May 23. pii: S0091-6749(17)30672-3. doi: 10.1016/j.jaci.2017.04.006. [Epub ahead of print]

Wang, L., Haug, P. J., & Del Fiol, G. (2017). Using classification models for the generation of disease-specific medications from biomedical literature and clinical data repository. J Biomed Inform, 69, 259-266.  doi:10.1016/j.jbi.2017.04.014

Kowalski LT, Goss FR, Landman AB, Hassid S, Meteer M, Blackley SV, Bates DW, Zhou L. Front-End vs. Back-End Clinical Document Dictation Preferences among Physicians at a Large Integrated Healthcare System. SGIM 2017 Annual Meeting; 2017 April 19-22, Washington, DC.

Banerji A, Blumenthal KG, Lai KH, Zhou L. Epidemiology of ACE Inhibitor Angioedema Utilizing a Large Electronic Health Record. J Allergy Clin Immunol Pract. 2017 Apr 1. pii: S2213-2198(17)30163-0. doi: 10.1016/j.jaip.2017.02.018. [Epub ahead of print]

Navathe AS, Zhong F, Lei VJ, Chang FY, Sordo M, Topaz M, Navathe SB, Rocha RA, Zhou L. Hospital Readmission and Social Risk Factors Identified from Physician Notes. Health Serv Res. 2017 Mar 13. doi: 10.1111/1475-6773.12670. [In Press]

Wang, L., Del Fiol, G., Bray, B. E., & Haug, P. J. (2017). Generating disease-pertinent treatment vocabularies from MEDLINE citations. J Biomed Inform, 65, 46-57. doi:10.1016/j.jbi.2016.11.004

Blumenthal KG, Acker WW, Li Y, Holtzman NS, Zhou L. Allergy entry and deletion in the electronic health record. Ann Allergy Asthma Immunol. 2017 Mar;118(3):380-381. doi: 10.1016/j.anai.2016.12.020. Epub 2017 Jan 23.

Zhou L, Collins S, Morgan SJ, Zafar N, Gesner EJ, Fehrenbach M, Rocha RA. A Decade of Experience in Creating and Maintaining Data Elements for Structured Clinical Documentation in EHRs. AMIA Annu Symp Proc. 2017 Feb 10;2016:1293-1302. eCollection 2016. PubMed PMID: 28269927; PubMed Central PMCID: PMC5333263.

Blumenthal KG, Lai KH, Huang M, Wallace ZS, Wickner PG, Zhou L. Adverse and Hypersensitivity Reactions to Prescription Nonsteroidal Anti-Inflammatory Agents in a Large Health Care System. J Allergy Clin Immunol Pract. 2017 Jan 18. pii: S2213-2198(16)30669-9. doi: 10.1016/j.jaip.2016.12.006. PubMed PMID: 28110055.

Topaz M, Goss F, Blumenthal K, Lai K, Seger DL, Slight SP, Wickner PG, Robinson GA, Fung KW, McClure RC, Spiro S, Acker WW, Bates DW, Zhou L. Towards improved drug allergy alerts: multidisciplinary expert recommendations. Int J Med Inform. 2017 Jan;97:353-355. doi: 10.1016/j.ijmedinf.2016.10.006. Epub 2016 Oct 6.


Guangjun Yu, Wenbin Cui, Li Zhou, D. W. Bates, Jianlei Gu and Hui Lu, “Implementation of a city-wide Health Information Exchange solution in the largest metropolitan region in China,” 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Shenzhen, 2016, pp. 795-798. doi: 10.1109/BIBM.2016.7822626.

Topaz M, Lai K, Lei VJ, Dowding D, Zisberg A, Bowles KH, Zhou L. Automated identification of wound information in clinical notes of patients with heart diseases: developing and validating a natural language processing application. Int J Nurs Stud. 2016 Dec;64:25-31. doi: 10.1016/j.ijnurstu.2016.09.013. Epub 2016 Sep 19.

Zhou L, Acker WW, Landman AB, Kontrient E, Doan R, Blackley SV, Mack D, Bates DW, Goss FR. An error analysis of dictated clinical documents at different processing stages. AMIA 2016 Annual Symposium; 2016 Nov 12-16, Chicago, IL.

Lai KH, Riley CS, Blackley SV, Zhou L. Automated classification of symptom severity in initial psychiatric evaluations. 2016 CEGS N-GRID Shared-Tasks and Workshop on Challenges in Natural Language Processing for Clinical Data; 2016 Nov 11, Chicago, IL.

Topaz M, Goss F, Blumenthal K, Lai K, Seger DL, Slight SP, Wickner PG, Robinson GA, Fung KW, McClure RC, Spiro S, Acker WW, Bates DW, Zhou L. Expert recommendations on redesigning drug allergy alerts in electronic health record systems. AMIA 2016 Annual Symposium; 2016 Nov 12-16, Chicago, IL.

Topaz M, Radhakrishnan K, Blackley S, Lei V, Lai K, Zhou L. Studying associations between heart failure self-management and rehospitalizations using natural language processing. West J Nurs Res. 2016 Sep 14. pii: 0193945916668493. [Epub ahead of print]

Goss FR, Zhou L, Weiner SG. Incidence of speech recognition errors in the emergency department. Int J Med Inform. 2016 Sep;93:70-3. doi: 10.1016/j.ijmedinf.2016.05.005. Epub 2016 May 26.

Zhou L, Dhopeshwarkar N, Blumenthal KG, Goss F, Topaz M, Slight SP, Bates DW. Drug allergies documented in electronic health records of a large healthcare system. Allergy. 2016 Sep;71(9):1305-13. doi: 10.1111/all.12881. Epub 2016 Apr 6.

Navathe AS, Zhong F, Lei V, Chang FY, Rocha RA, Zhou L. Identifying patients at high-risk for readmission using socio-behavioral patient characteristics. AcademyHealth 2016 Annual Research Meeting; 2016 Jun 26-28, Boston, MA.

Topaz M, Radhakrishnan K, Lei V, Zhou L. Mining Clinicians’ Electronic Documentation to Identify Heart Failure Patients with Ineffective Self-Management: A Pilot Text-Mining Study. Stud Health Technol Inform. 2016; 225:856-7. PMID: 27332377.

Topaz M, Radhakrishnan K, Lei V, Zhou L. Mining clinicians’ electronic documentation to identify heart failure patients with ineffective self-management: a pilot text-mining study. 13th International Congress in Nursing Informatics (NI2016); 2016 Jun 25-29, Geneva, Switzerland.

Navathe A, Zhong F, Lei VJ, Chang Y, Zhou L. Improving prediction of patients at high-risk for readmission using data from physician notes. 6th Biennial Conference of the American Society of Health Economists (ASHEcon 2016); 2016 Jun 12-15, Philadelphia, PA.

Navathe AS, Zhong F, Lei V, Chang FY, Rocha RA, Zhou L. Improving identification of patients at high-risk for readmission using socio-behavioral patient characteristics. SGIM 2016 Annual Meeting; 2016 May 11-14, Hollywood, FL.

Topaz M, Seger DL, Slight SP, Goss F, Lai K, Wickner PG, Blumenthal K, Dhopeshwarkar N, Chang F, Bates DW, Zhou L. Rising drug allergy alert overrides in electronic health records: an observational retrospective study of a decade of experience. J Am Med Inform Assoc. 2016 May;23(3):601-8. doi: 10.1093/jamia/ocv143. Epub 2015 Nov 17.

Plasek JM, Goss FR, Lai KH, Lau JJ, Seger DL, Blumenthal KG, Wickner PG, Slight SP, Chang FY, Topaz M, Bates DW, Zhou L. Food entries in a large allergy data repository. J Am Med Inform Assoc. 2016 Apr;23(e1):e79-87. doi: 10.1093/jamia/ocv128. Epub 2015 Sep 17.

Banerji A, Blumenthal KG, Lai KH, Zhou L. Epidemiology and incidence of ACE inhibitor angioedema utilizing a large electronic health record. AAAAI 2016 Annual Meeting; 2016 Mar 4-7, Los Angeles, CA.

Blumenthal KG, Lai KH, Topaz M, Wickner PG, Seger DL, Goss FR, Slight SP, Chang FY, Zhou L. Reported incidence of hypersensitivity reactions to non-steroidal anti-inflammatory drugs in the electronic health record. AAAAI 2016 Annual Meeting; 2016 Mar 4-7, Los Angeles, CA.

Topaz M, Lai K, Dhopeshwarkar N, Seger DL, Sa’adon R, Goss F, Rozenblum R, Zhou L. Clinicians’ reports in electronic health records versus patients’ concerns in social media: a pilot study of adverse drug reactions of aspirin and atorvastatin. Drug Saf. 2016 Mar;39(3):241-50. doi: 10.1007/s40264-015-0381-x.

Wang, L., Bray, B. E., Shi, J., Del Fiol, G., & Haug, P. J. (2016). A method for the development of disease-specific reference standards vocabularies from textual biomedical literature resources. Artif Intell Med, 68, 47-57. doi:10.1016/j.artmed.2016.02.003

Topaz M, Seger DL, Goss F, Lai K, Slight SP, Lau JJ, Nandigam H, Zhou L. Standard information models for representing adverse sensitivity information in clinical documents. Methods Inf Med. 2016;55(2):151-7. doi: 10.3414/ME15-01-0081. Epub 2016 Feb 24.


Zhou L, Topaz M, Seger DL, Slight SP, Goss F, Lai K, Wickner PG, Blumenthal K, Dhopeshwarkar N, Chang F, Bates DW. Rising drug allergy alert overrides in a computerized provider order entry system: a decade of experience. AMIA 2015 Annual Symposium; 2015 Nov 14-18, San Francisco, CA.

Topaz M, Lai K, Lei VJ, Dowding D, Zisberg A, Bowles KH, Zhou L. Creating a natural language processing algorithm to identify wound information in narrative clinical notes. Home Healthcare and Hospice Information Technology Conference (H3IT 2015); 2015 Oct 27, Nashville, TN.

Topaz M, Seger DL, Lai K, Wickner PG, Goss F, Dhopeshwarkar N, Chang F, Bates DW, Zhou L. High override rate for opioid drug-allergy interaction alerts: current trends and recommendations for future. 15th World Congress on Health and Biomedical Informatics (MEDINFO 2015); 2015 Aug 19-23, São Paulo, Brazil.

Zhou L, Baughman AW, Lei VJ, Lai KH, Navathe AS, Chang F, Sordo M, Topaz M, Zhong F, Murrali M, Navathe S, Rocha RA. Identifying Patients with Depression Using Free-text Clinical Documents. Stud Health Technol Inform. 2015;216:629-33. PMID: 26262127. — Received Best Paper Award Nomination in Medinfo – The 15th World Congress on Medical and Health Informatics / IMIA, São Paulo, Brazil, 2015

Lai KH, Topaz M, Goss FR, Zhou L. Automated misspelling detection and correction in clinical free-text records. J Biomed Inform. 2015 Jun;55:188-95. doi: 10.1016/j.jbi.2015.04.008. Epub 2015 Apr 24.

Topaz M, Lai K, Dhopeshwarkar N, Seger D, Sa’adon R, Goss F, Rozenblum R, Zhou L. Do patients and clinicians share the same concerns? Aspirin and Lipitor adverse drug reactions in electronic health records and social media. Sağlık Bilişim Zirvesi [Health IT Summit]; 2015 May 8-9, İstanbul, Turkey.

Blumenthal KG, Wickner PG, Lau JJ, Zhou L. Stevens-Johnson syndrome and toxic epidermal necrolysis: a cross-sectional analysis of patients in an integrated allergy repository of a large health care system. J Allergy Clin Immunol Pract. 2015 Mar-Apr;3(2):277-280.e1. doi: 10.1016/j.jaip.2014.10.002. Epub 2014 Nov 18.


Goss FR, Plasek JM, Lau JJ, Seger DL, Chang FY, Zhou L. An evaluation of a natural language processing tool for identifying and encoding allergy information in emergency department clinical notes. AMIA 2014 Annual Symposium; 2014 Nov 15-19, Washington, DC.

Zhou L, Lu Y, Vitale CJ, Mar P, Chang F, Dhopeshwarkar N, Rocha RA. Representation of Information about Family Relatives as Structured Data in Electronic Health Records. Applied Clinical Informatics. 2014; 5(2): 349-267. PMID:25024754


Zhou L, Hongsermeier T, Boxwala A, Lewis J, Kawamoto K, Maviglia S, Gentile D, Teich JM, Rocha R, Bell D, Middleton B. Structured representation for core elements of common clinical decision support interventions to facilitate knowledge sharing. Stud Health Technol Inform. 2013; 192:195-9. PMID: 23920543 — Received Distinguished Paper Award in Medinfo – The 14th World Congress on Medical and Health Informatics / IMIA, Copenhagen, Denmark, 2013

Shu T, Liu H, Goss FR, Y Wei, Zhou L, Bates DW, Liang M. EHR adoption across China’s tertiary hospitals: A cross-sectional observational study. International Journal of Medical Informatics, In Press, Available online 1 September 2013. PMID: 24262068

Goss FR*, Zhou L*, Plasek JM, Broverman C, Robinson G, Middleton B, Rocha RA. Evaluating standard terminologies for encoding allergy information. J Am Med Inform Assoc. 2013: 20(5):969-79. (*co-first author) PMID:23396542.


Zhou L, Maviglia SM, Mahoney LM, Chang F, Orav, EJ, Plasek J, Boulware LJ, Lou H, Bates DW, Rocha RA. Supratherapeutic Dosing of Acetaminophen among Hospitalized Patients. Arch Intern Med. 2012 Dec 10;172(22):1721-8. PMID: 23401887.

Zhou L, Karipineni N, Lewis J, Maviglia SM, Fairbanks A, Hongsermeier T, Middleton B, Rocha RA. A study of diverse clinical decision support rule authoring environments and requirements for integration. BMC Med Inform Decis Mak. 2012 Nov 12;12(1):128. PMID: 23145874 [Online]

Zhou L, Plasek JM, Mahoney LM, Chang F, Dimaggio D, Rocha RA. Mapping Partners Master Drug Dictionary to RxNorm Using an NLP-based Approach. J Biomed Inform. 2012;45(4):626-33. PMID:22142948.


Zhou L, Plasek JM, Mahoney LM, Karipineni N, Chang F, Yan X, Chang F, Dimaggio D, Goldman DS, Rocha RA. Using Medical Text Extraction, Reasoning and Mapping System (MTERMS) to process medication information in outpatient clinical notes. AMIA Annu Symp Proc. 2011;2011:1639-48. Epub 2011 Oct 22.

Hripcsak, G., Knirsch, C., Zhou, L., Wilcox, A., & Melton, G. Bias Associated with Mining Electronic Health Records. J Biomed Discov Collab. 2011; 6: 48–52. PMID: 21647858.


Zhou L, Soran CS, Jenter CA, Volk LA, Orav EJ, Bates DW, Simon SR. The Relationship between Electronic Health Record Use and Quality of Care over Time. J Am Med Inform Assoc 2009; 16(4): 457-64. PMID: 19390094.

Zhou L, Goldberg H, Pabbathi D, Wright A, Goldman DS, Van Putten C, Barley A, Rocha RA. Terminology Modeling for an Enterprise Laboratory Orders Catalog. AMIA Annu Symp Proc. 2009 Nov:735-739. PMID: 20351950.

=< 2008

Chen ES, Zhou L, Kashyap V, Schaeffer M, Dykes PC, Goldberg HS. Early Experiences in Evolving an Enterprise-Wide Information Model for Laboratory and Clinical Observations. AMIA Annu Symp Proc. 2008 Nov 6:106-10. PMID: 18999078.

Zhou L, Parsons S, Hripcsak G. The Evaluation of a Temporal Reasoning System in Processing Clinical Discharge Summaries. J Am Med Inform Assoc 2008 Jan-Feb; 15(1): 99-106. PMID: 17947618.

Zhou L, Tao Y, Cimino JJ, Chen ES, Liu H, Lussier YA, Hripcsak G, Friedman C. Terminology Model Discovery Using Natural Language Processing and Visualization Techniques. J Biomed Inform 2006 Dec;39(6):626-36. PMID: 16360342.

Zhou L, Melton G, Parsons S, Hripcsak G. A Temporal Constraint Structure for Extracting Temporal Information from Clinical Narrative. J Biomed Inform 2006 Aug; 39(4):424-439. PMID: 16169282.

Zhou L, Hripcsak G. Temporal Reasoning with Medical Data – A Review with Emphasis on Medical Natural Language Processing. J Biomed Inform 2007 Apr;40(2):183-202. PMID: 17317332.

Zhou L, Friedman C, Parsons S, Hripcsak G. System Architecture for Temporal Information Extraction, Representation and Reasoning in Clinical Narrative Reports. AMIA Annu Symp Proc. 2005; 869-873. PMID: 16779164.